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Rose was raised in Titirangi, Auckland, by her photographer father and artist mother. She studied Psychology and Linguistics at the University of Auckland.
At the age of two, Rose began appearing in commercials and received the role of an angel in the film The Piano at age three. She has worked mainly for New Zealand television, from fantasy-based series like Maddigan's Quest to dramas such as Rude Awakenings, as well as two Disney Channel films.
Rose's big-screen debut was in Peter Jackson's film, The Lovely Bones, playing Lindsey Salmon, the younger sister of the main character. She appeared in the 2010 film Predicament and the television film Tangiwai, based on the 1953 Tangiwai rail disaster. In 2014, she starred as Olivia Moore in the series iZombie, which ran for five seasons.
Rose enjoys writing, crossword puzzles and Sudoku. She is an ambassador for Emirates airlines.