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Covid: Model shows that ICU overload risks 'thousands' more of deaths

Author
Jamie Morton, NZ Herald,
Publish Date
Sun, 22 Mar 2020, 4:49PM
(Photo / AP)
(Photo / AP)

Covid: Model shows that ICU overload risks 'thousands' more of deaths

Author
Jamie Morton, NZ Herald,
Publish Date
Sun, 22 Mar 2020, 4:49PM

An overload of New Zealand's intensive-care units could mean the difference between tens of thousands of coronavirus patients dying, new modelling indicates.

The Ministry of Health is aware of the risk, and has moved to meet it by putting in place a four-stage alert system, and expanding the country's ICU capacity.

Researchers at Te PÅ«naha Matatini, New Zealand's Centre of Research Excellence in Complex Systems and Data Analytics, have been developing models that show what hit the health system could be in for.

The centre's director, Professor Shaun Hendy, said based on overseas data, around 10 per cent of people who catch Covid-19 would need to be hospitalised, and around one quarter of those cases would need intensive care to survive.

"If we don't take measures to control Covid-19 then our model suggests that the number of people needing intensive care will be about 10 times the capacity of our hospitals, which will mean many tens of thousands of fatalities," Hendy said.

"It is crucial to ensure we have enough intensive-care beds, as well as the healthcare workers to manage them, so that people receive the care they need to keep them alive."

Some early, but simple, models threw up the potential for 100,000 hospitalisations and 25,000 deaths.

Another initial model his colleagues built – assuming there was 300 ICU beds, which was a third more than current numbers – showed an overload of ICU beds would mean the difference between death rates of one and two per cent of all cases.

Hendy said the difference between taking strong measures could see 10,000 deaths, versus 60,000 deaths and a 80 to 90 per cent infection rate if nothing was done.

Today, Ministry of Health director-general of health Dr Ashley Bloomfield said such modelling was "very helpful", in that it showed what would happen if New Zealand didn't act quickly and with certainty.

New Zealand was at level two of its four-stage alert system to manage the pandemic.

"The reason that [levels] three and four are there is because we are signalling that we may well need to move to those - and the reason we would move to those is to avoid a situation where we overloaded our healthcare system, including ICU capacity."

Hendy said that had scenario had already played out in Italy, forcing doctors to choose who received intensive care - or effectively, who survived.

"That is a horrible position to be in, and it means the fatality rate will be higher than it would be if they had more ICU capacity or had adopted an aggressive suppression strategy earlier on," he said.

The "suppression" strategy was one of two approaches outlined in a new report, by Imperial College London (ICL) researchers, which has prompted many governments – including New Zealand – to rethink their approach.

This graph in the Imperial College London report shows

This graph in the Imperial College London report shows "mitigation" strategy scenarios for Great Britain showing critical care (ICU) bed requirements. The black line shows the unmitigated epidemic. The green line shows a mitigation strategy incorporating closure of schools and universities; orange line shows case isolation; yellow line shows case isolation and household quarantine; and the blue line shows case isolation, home quarantine and social distancing of those aged over 70. The blue shading shows the 3-month period in which these interventions are assumed to remain in place. Image / ICL

That aimed to stamp out the spread as much as possible until a vaccine arrived, through tough control measures like isolation, quarantine, social distancing and school closures early, before an outbreak could take off.

The other approach – mitigation – allowed the disease to spread, but with measures to isolate suspected cases and those at risk like elderly, so the rate would be slowed enough for hospitals to cope.

The ICL analysis found suppression would have a better chance of sparing the health system from overloads – and New Zealand officials were now looking to manage any outbreak through a series of smaller, controlled surges rather than one "flattened" peak.

"The best approach, we think, is to adopt aggressive suppression measures as soon as practicable."

Hendy added there was still much to be learnt about the virus, and some of the data that was coming in from other countries might not be as applicable to New Zealand as time went on.

"Also, we have used a relatively simple model, which effectively treats New Zealand as one big city where anyone has the chance of infecting anyone else in the country," he said.

"What we want to do next is to build a regional model so we could see what the effect of quarantining or restricting movement in different parts of the country might be. This might allow us to use a containment strategy similar to those being used in South Korea."

Last week, Bloomfield said the country's approach had pivoted from trying to flatten one large peak of cases, to using controls to manage a series of peaks to assist the healthcare system.

All models had shown that one single wave of transmission - or peak - would cause cases to take off.

The ICL report had been "very crucial" in changing tack to prevent that happening.

"Our approach is – and this is what successful countries have done – is you want to have a series of small peaks over a long period of time."

Hendy pointed out that mitigation strategies relied only on getting R0 – or the average number of people who catch the disease from each infected person - below one.

"Only China and South Korea have managed to do that, so it would be risky to rely on a mitigation strategy alone."

The number of ICU beds per population in New Zealand has fallen steadily over the last 20 years, with the country now well behind comparable countries, including Australia.

The Ministry of Health has already acknowledged the current capacity might not meet demand for a widespread Covid-19 outbreak and last Tuesday announced a $32 million boost, though experts have questioned if it will be enough to bridge the gap.

The percentage of those who could catch the virus is highly variable, but many estimates fall around 40 to 60 per cent of the global population.

According to the Ministry of Health, New Zealand has 176 intensive-care unit beds and 57 high-dependency and cardiac care beds spread across the country's 20 DHBs.

Based on those numbers, several thousand cases could overwhelm New Zealand's health system - provided all of those beds were available for Covid-19 patients, and assuming they all contained the necessary equipment.

To manage increase in demand, doctors have told the Herald that New Zealand could see elective surgeries shut down and hospitals bring in extra resources, such as converting theatres to ICU wards.

Officials were looking at all options - including repurposing older ventilators that had been recently replaced in upgrades.

"As well, we need to train staff to look after people who are being ventilated 24/7," Bloomfield said.

 

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