The Trans Pacific Partnership appears another step closer.
Twelve countries, including New Zealand, have wrapped up the latest round of talks in Sydney.
In a joint statement, the ministers say the shape of an ambitious, comprehensive, high standard and balanced deal is crystallising.
They say they are working closely to resolve outstanding issues.
Over the past four years, the negotiations have been criticised by medical and intellectual property rights experts.
Australia's Trade Minister has rejected criticism that the deal will add to the cost of pharmaceuticals.
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